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Magtein’s Effect on Stress & Anxiety in a Taste Aversion Model

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By: Sean Moloughney

Editor, Nutraceuticals World

A newly published study, performed by a research group at Baldwin Wallace University, independently demonstrated that proprietary ingredient Magtein—which is designed to improve memory, recognition and learning—enhanced the memory lead to the consolidation and retention of conditioned taste aversion (CTA) in rats. The study was led by G. Andrew Mickley, Ph.D. of The Neuroscience Program at Baldwin Wallace University, Berea, Ohio, and published in Pharmacology Biochemistry Behavior, March 6, 2013.
 
According to Jennifer Gu, Ph.D., AIPD vice president of research and development, this study, which was not commissioned by AIDP, provided verification by independent research of previously published functions of Magtein in a different behavior system that has been known to use the same brain signaling pathways. Magtein helps maintain the health of the neuron cells and increases neural plasticity. The test reaffirms that continued Magtein supplementation can help to control stress or anxiety, plus increase memory and cognitive functions by elevating brain’s magnesium levels.
 
Previous published studies have shown that Magtein was able to effectively increase brain’s magnesium levels, leading to improved learning and working memories, as well as controlling the fear memory.
This study examined the effects of Magtein, a novel, self-affirmed GRAS, non-GMO magnesium compound, on controlled taste aversion (CTA) extinction and spontaneous recovery. Adult male Sprague-Dawley rats acquired a CTA following the taste of saccharin paired with lithium chloride (LiCl) injection. Magtein-fed animals were shown to significantly improve their ability to speed CTA extinction, as compared to the control animals.
 
The purpose of the study was to examine the ability of Magtein to affect the extinction and spontaneous recovery (SR) on conditioned taste aversion (CTA). Researchers created an aversive memory that caused the rats to refuse the conditioned stimulus (CS) of saccharin. This aversion memory was then slowly extinguished by repeated exposure to saccharin alone. Magtein treated rats exhibited a faster rate of extinction than the control group.
 
“The clinical trial results revealed that the effect of Magtein on memory enhancement as well as fear memory control was proven in a different system by an independent third party research group,” said Dr. Gu.
 
“While further studies are needed, the data suggests that Magtein may enhance many areas of the memory related brain functions, as covered by awarded and pending international patents. We are optimistic that more independent studies will confirm and reveal further applicable functions of Magtein,” she added. 
 
For more information: www.AIDP.com

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